Gonad morphogenesis in Caenorhabditis elegans requires two secreted proteases. Recent studies show that alterations of the extracellular matrix component fibulin-1 rescue gonadogenesis in the absence of these proteases. This finding is a critical step toward understanding the role of extracellular matrix in organogenesis.
All Science Journal Classification (ASJC) codes
- General Biochemistry, Genetics and Molecular Biology
- General Agricultural and Biological Sciences