Organization of transcription units around the Drosophila melanogaster rudimentary locus and temporal pattern of expression

J. M. Rawls; J. N. Freund; B. P. Jarry; C. Louis; W. A. Segraves; P. Schedl

doi:10.1007/BF00333283

Organization of transcription units around the Drosophila melanogaster rudimentary locus and temporal pattern of expression

J. M. Rawls, J. N. Freund, B. P. Jarry, C. Louis, W. A. Segraves, P. Schedl

Molecular Biology

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14 Scopus citations

Abstract

The molecular organization of 90 kb of DNA derived from a region of the X chromosome that encompasses the rudimentary locus of D. melanogaster is presented. This segment spans the cytogenetic region 14F2-3 to 15A1-2, and there are, in addition to the rudimentary gene several transcription units present, whose functions are still unknown. We have determined the pattern of expression of all these genes at several stages of development, and found that they all show a different temporal modulation of their activity. The accumulation of the r product correlated well with the enzymatic activity determined for the protein product of the gene, being highest in very early embryos and adult females.

Original language	English (US)
Pages (from-to)	493-499
Number of pages	7
Journal	MGG Molecular & General Genetics
Volume	202
Issue number	3
DOIs	https://doi.org/10.1007/BF00333283
State	Published - Mar 1986

All Science Journal Classification (ASJC) codes

Genetics

Keywords

Gene expression
Northern blots
Polytene chromosomes

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10.1007/BF00333283

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title = "Organization of transcription units around the Drosophila melanogaster rudimentary locus and temporal pattern of expression",

abstract = "The molecular organization of 90 kb of DNA derived from a region of the X chromosome that encompasses the rudimentary locus of D. melanogaster is presented. This segment spans the cytogenetic region 14F2-3 to 15A1-2, and there are, in addition to the rudimentary gene several transcription units present, whose functions are still unknown. We have determined the pattern of expression of all these genes at several stages of development, and found that they all show a different temporal modulation of their activity. The accumulation of the r product correlated well with the enzymatic activity determined for the protein product of the gene, being highest in very early embryos and adult females.",

keywords = "Gene expression, Northern blots, Polytene chromosomes",

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year = "1986",

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T1 - Organization of transcription units around the Drosophila melanogaster rudimentary locus and temporal pattern of expression

AU - Rawls, J. M.

AU - Freund, J. N.

AU - Jarry, B. P.

AU - Louis, C.

AU - Segraves, W. A.

AU - Schedl, P.

PY - 1986/3

Y1 - 1986/3

N2 - The molecular organization of 90 kb of DNA derived from a region of the X chromosome that encompasses the rudimentary locus of D. melanogaster is presented. This segment spans the cytogenetic region 14F2-3 to 15A1-2, and there are, in addition to the rudimentary gene several transcription units present, whose functions are still unknown. We have determined the pattern of expression of all these genes at several stages of development, and found that they all show a different temporal modulation of their activity. The accumulation of the r product correlated well with the enzymatic activity determined for the protein product of the gene, being highest in very early embryos and adult females.

AB - The molecular organization of 90 kb of DNA derived from a region of the X chromosome that encompasses the rudimentary locus of D. melanogaster is presented. This segment spans the cytogenetic region 14F2-3 to 15A1-2, and there are, in addition to the rudimentary gene several transcription units present, whose functions are still unknown. We have determined the pattern of expression of all these genes at several stages of development, and found that they all show a different temporal modulation of their activity. The accumulation of the r product correlated well with the enzymatic activity determined for the protein product of the gene, being highest in very early embryos and adult females.

KW - Gene expression

KW - Northern blots

KW - Polytene chromosomes

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Organization of transcription units around the Drosophila melanogaster rudimentary locus and temporal pattern of expression

Abstract

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