Integrative recombination of phage λ DNA occurs in extracts made from cells synthesizing int protein. In this paper we show that extracts of cells containing temperature-sensitive int protein are inactivated more rapidly by incubation at 38 °C than are wild-type extracts. This indicates that the int protein is directly involved in the recombination reaction.
All Science Journal Classification (ASJC) codes
- Structural Biology
- Molecular Biology