On the role of the bacteriophage λ int gene product in site specific recombination

Howard A. Nash; Lynn W. Enquist; Robert A. weisberg

doi:10.1016/0022-2836(77)90091-2

On the role of the bacteriophage λ int gene product in site specific recombination

Howard A. Nash, Lynn W. Enquist, Robert A. weisberg

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Abstract

Integrative recombination of phage λ DNA occurs in extracts made from cells synthesizing int protein. In this paper we show that extracts of cells containing temperature-sensitive int protein are inactivated more rapidly by incubation at 38 °C than are wild-type extracts. This indicates that the int protein is directly involved in the recombination reaction.

Original language	English (US)
Pages (from-to)	627-631
Number of pages	5
Journal	Journal of Molecular Biology
Volume	116
Issue number	3
DOIs	https://doi.org/10.1016/0022-2836(77)90091-2
State	Published - Nov 5 1977

All Science Journal Classification (ASJC) codes

Biophysics
Structural Biology
Molecular Biology

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10.1016/0022-2836(77)90091-2

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title = "On the role of the bacteriophage λ int gene product in site specific recombination",

abstract = "Integrative recombination of phage λ DNA occurs in extracts made from cells synthesizing int protein. In this paper we show that extracts of cells containing temperature-sensitive int protein are inactivated more rapidly by incubation at 38 °C than are wild-type extracts. This indicates that the int protein is directly involved in the recombination reaction.",

author = "Nash, {Howard A.} and Enquist, {Lynn W.} and weisberg, {Robert A.}",

year = "1977",

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AU - Nash, Howard A.

AU - Enquist, Lynn W.

AU - weisberg, Robert A.

PY - 1977/11/5

Y1 - 1977/11/5

N2 - Integrative recombination of phage λ DNA occurs in extracts made from cells synthesizing int protein. In this paper we show that extracts of cells containing temperature-sensitive int protein are inactivated more rapidly by incubation at 38 °C than are wild-type extracts. This indicates that the int protein is directly involved in the recombination reaction.

AB - Integrative recombination of phage λ DNA occurs in extracts made from cells synthesizing int protein. In this paper we show that extracts of cells containing temperature-sensitive int protein are inactivated more rapidly by incubation at 38 °C than are wild-type extracts. This indicates that the int protein is directly involved in the recombination reaction.

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ER -

On the role of the bacteriophage λ int gene product in site specific recombination

Abstract

All Science Journal Classification (ASJC) codes

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