On the role of the bacteriophage λ int gene product in site specific recombination

Howard A. Nash, Lynn William Enquist, Robert A. weisberg

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Integrative recombination of phage λ DNA occurs in extracts made from cells synthesizing int protein. In this paper we show that extracts of cells containing temperature-sensitive int protein are inactivated more rapidly by incubation at 38 °C than are wild-type extracts. This indicates that the int protein is directly involved in the recombination reaction.

Original languageEnglish (US)
Pages (from-to)627-631
Number of pages5
JournalJournal of Molecular Biology
Volume116
Issue number3
DOIs
StatePublished - Nov 5 1977
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Virology

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