Novel Pyrrolo[3,2-d]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy

Aamod S. Dekhne, Khushbu Shah, Gregory S. Ducker, Jade M. Katinas, Jennifer Wong-Roushar, Md Junayed Nayeen, Arpit Doshi, Changwen Ning, Xun Bao, Josephine Fruhauf, Jenney Liu, Adrianne Wallace-Povirk, Carrie O'Connor, Sijana H. Dzinic, Kathryn White, Juiwanna Kushner, Seongho Kim, Maik Huttemann, Lisa Polin, Joshua D. RabinowitzJing Li, Zhanjun Hou, Charles E. Dann, Aleem Gangjee, Larry H. Matherly

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Medicine & Life Sciences