Neurogenesis in the neocortex of adult primates

Elizabeth Gould, Alison J. Reeves, Michael S.A. Graziano, Charles G. Gross

Research output: Contribution to journalArticle

1008 Scopus citations

Abstract

In primates, prefrontal, inferior temporal, and posterior parietal cortex are important for cognitive function. It is shown that in adult macaques, new neurons are added to these three neocortical association areas, but not to a primary sensory area (striate cortex). The new neurons appeared to originate in the subventricular zone and to migrate through the white matter to the neocortex, where they extended axons. These new neurons, which are continually added in adulthood, may play a role in the functions of association neocortex.

Original languageEnglish (US)
Pages (from-to)548-552
Number of pages5
JournalScience
Volume286
Issue number5439
DOIs
StatePublished - Oct 15 1999

All Science Journal Classification (ASJC) codes

  • General

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