Natural selection, genetic variation, and human diversity

Leslie S. Emery, Joshua M. Akey

Research output: Chapter in Book/Report/Conference proceedingChapter


Patterns of human genetic diversity observed in present-day individuals provide insight into our species evolutionary history and regions of the genome that have been influenced by natural selection. In this chapter, we discuss methods and models that have been used to better understand how selection has impacted human variation and review studies of natural selection in humans and the stories they reveal about human history.

Original languageEnglish (US)
Title of host publicationHuman Population Genomics
Subtitle of host publicationIntroduction to Essential Concepts and Applications
PublisherSpringer International Publishing
Number of pages30
ISBN (Electronic)9783030616465
ISBN (Print)9783030616441
StatePublished - Apr 14 2021

All Science Journal Classification (ASJC) codes

  • General Biochemistry, Genetics and Molecular Biology
  • General Mathematics
  • General Medicine


  • Adaptive evolution
  • Evolution
  • Genetic variation
  • Natural selection
  • Positive selection


Dive into the research topics of 'Natural selection, genetic variation, and human diversity'. Together they form a unique fingerprint.

Cite this