Abstract
Patterns of human genetic diversity observed in present-day individuals provide insight into our species evolutionary history and regions of the genome that have been influenced by natural selection. In this chapter, we discuss methods and models that have been used to better understand how selection has impacted human variation and review studies of natural selection in humans and the stories they reveal about human history.
Original language | English (US) |
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Title of host publication | Human Population Genomics |
Subtitle of host publication | Introduction to Essential Concepts and Applications |
Publisher | Springer International Publishing |
Pages | 205-234 |
Number of pages | 30 |
ISBN (Electronic) | 9783030616465 |
ISBN (Print) | 9783030616441 |
DOIs | |
State | Published - Apr 14 2021 |
All Science Journal Classification (ASJC) codes
- General Biochemistry, Genetics and Molecular Biology
- General Mathematics
- General Medicine
Keywords
- Adaptive evolution
- Evolution
- Genetic variation
- Natural selection
- Positive selection