TY - JOUR

T1 - Narrow escape, part III

T2 - Non-smooth domains and Riemann surfaces

AU - Singer, A.

AU - Schuss, Z.

AU - Holcman, D.

N1 - Funding Information:
This research was partially supported by research grants from the Israel Science Foundation, US-Israel Binational Science Foundation, and the NIH Grant No. UPSHS 5 RO1 GM 067241. D. H. is incumbent to the Madeleine Haas Russell Career Development Chair, his research is partially supported by the program “Chaire d’Excellence.” The authors thank R.S. Eisenberg for critical review of the manuscript.

PY - 2006/2

Y1 - 2006/2

N2 - We consider the narrow escape problem in two-dimensional Riemannian manifolds (with a metric g) with corners and cusps, in an annulus, and on a sphere. Specifically, we calculate the mean time it takes a Brownian particle diffusing in a domain Ω to reach an absorbing window when the ratio ε = |∂Ωa|g/|∂Ω|g| between the absorbing window and the otherwise reflecting boundary is small. If the boundary is smooth, as in the cases of the annulus and the sphere, the leading term in the expansion is the same as that given in part I of the present series of papers, however, when it is not smooth, the leading order term is different. If the absorbing window is located at a corner of angle α, then Eτ = |Ω|g/αD[log 1/ε + O(1)], if near a cusp, then Eτ grows algebraically, rather than logarithmically. Thus, in the domain bounded between two tangent circles, the expected lifetime is Eτ = |Ω|/(d -1-1)D(1/ε + O(1)), where d < 1 is the ratio of the radii. For the smooth boundary case, we calculate the next term of the expansion for the annulus and the sphere. It can also be evaluated for domains that can be mapped conformally onto an annulus. This term is needed in real life applications, such as trafficking of receptors on neuronal spines, because log 1/ε is not necessarily large, even when ε = |∂Ω a|g/|∂Ω|g| is small. In these two problems there are additional parameters that can be small, such as the ratio δ of the radii of the annulus. The contributions of these parameters to the expansion of the mean escape time are also logarithmic. In the case of the annulus the mean escape time is Eτ = |Ω|g/πD[log 1/ε + 1/2 log 1/δ+ O(1)].

AB - We consider the narrow escape problem in two-dimensional Riemannian manifolds (with a metric g) with corners and cusps, in an annulus, and on a sphere. Specifically, we calculate the mean time it takes a Brownian particle diffusing in a domain Ω to reach an absorbing window when the ratio ε = |∂Ωa|g/|∂Ω|g| between the absorbing window and the otherwise reflecting boundary is small. If the boundary is smooth, as in the cases of the annulus and the sphere, the leading term in the expansion is the same as that given in part I of the present series of papers, however, when it is not smooth, the leading order term is different. If the absorbing window is located at a corner of angle α, then Eτ = |Ω|g/αD[log 1/ε + O(1)], if near a cusp, then Eτ grows algebraically, rather than logarithmically. Thus, in the domain bounded between two tangent circles, the expected lifetime is Eτ = |Ω|/(d -1-1)D(1/ε + O(1)), where d < 1 is the ratio of the radii. For the smooth boundary case, we calculate the next term of the expansion for the annulus and the sphere. It can also be evaluated for domains that can be mapped conformally onto an annulus. This term is needed in real life applications, such as trafficking of receptors on neuronal spines, because log 1/ε is not necessarily large, even when ε = |∂Ω a|g/|∂Ω|g| is small. In these two problems there are additional parameters that can be small, such as the ratio δ of the radii of the annulus. The contributions of these parameters to the expansion of the mean escape time are also logarithmic. In the case of the annulus the mean escape time is Eτ = |Ω|g/πD[log 1/ε + 1/2 log 1/δ+ O(1)].

KW - Brownian motion on Riemannian manifolds

KW - Exit problem

KW - Singular perturbations

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U2 - 10.1007/s10955-005-8028-4

DO - 10.1007/s10955-005-8028-4

M3 - Article

AN - SCOPUS:33644521764

SN - 0022-4715

VL - 122

SP - 491

EP - 509

JO - Journal of Statistical Physics

JF - Journal of Statistical Physics

IS - 3

ER -