Abstract
We demonstrate continuous flow bifurcation of nanoparticles using the principle of deterministic lateral displacement. Recently arrays of microfabricated posts, tilted relative to the fluid flow direction, were successfully used to separate DNA fragments [1], microbeads [1,2] and to fractionate whole blood [3,4]. We scale down this technique using nanoimprint lithography (NIL) to pattern a large-area array of nanofabricated posts and demonstrate for the first time bifurcation of 100nm and 200nm diameter fluorescent particles.
Original language | English (US) |
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Pages | 1014-1016 |
Number of pages | 3 |
State | Published - 2006 |
Event | 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan Duration: Nov 5 2006 → Nov 9 2006 |
Other
Other | 10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 |
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Country/Territory | Japan |
City | Tokyo |
Period | 11/5/06 → 11/9/06 |
All Science Journal Classification (ASJC) codes
- Chemical Engineering (miscellaneous)
- Bioengineering
Keywords
- Etching
- Nanofluidics
- Nanoimprint lithography
- Separation
- Sorting