Abstract
We present a novel process for the production of three-layer Composite Nanoparticles (CNPs) in the size range 100-300 nm with an up-converting phosphor interior, a coating of porphyrin photosensitizer, and a biocompatible PEG outer layer to prevent clearance by the reticuloendothelial system. We show that these CNPs produce millimolar amounts of singlet oxygen at NIR intensities far less than other two-photon techniques.
Original language | English (US) |
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Pages (from-to) | 80-86 |
Number of pages | 7 |
Journal | Optics Express |
Volume | 17 |
Issue number | 1 |
DOIs | |
State | Published - Jan 5 2009 |
All Science Journal Classification (ASJC) codes
- Atomic and Molecular Physics, and Optics