N-Oxide-to-Carbon Transmutations of Azaarene N-Oxides

Nicholas A. Falcone, Sam He, John F. Hoskin, Sandeep Mangat, Erik J. Sorensen

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Reactions that change the identity of an atom within a ring system are emerging as valuable tools for the site-selective editing of molecular structures. Herein, we describe the expansion of an underdeveloped transformation that directly converts azaarene-derived N-oxides to all-carbon arenes. This ring transmutation exhibits good functional group tolerance and replaces the N-oxide moiety with either unsubstituted, substituted, or isotopically labeled carbon atoms in a single laboratory operation.

Original languageEnglish (US)
Pages (from-to)4280-4285
Number of pages6
JournalOrganic letters
Issue number20
StatePublished - May 24 2024

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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