We have combined techniques of genetic and physical mapping with rapid DNA sequence analysis to identify the nucleotide change in lambda int mutations. These mutations define two dominant phenotypic classes: (i) recombination that is partially independent of accessory factors, and (ii) inhibition of wild-type Int by missense or nonsense proteins, i.e., negative complementation.
|Original language||English (US)|
|Number of pages||4|
|Journal||Journal of bacteriology|
|State||Published - Dec 1987|
All Science Journal Classification (ASJC) codes
- Molecular Biology