Mutational analysis of the lambda int gene: DNA sequence of dominant mutations.

S. E. Bear; J. B. Clemens; L. W. Enquist; R. J. Zagursky

doi:10.1128/jb.169.12.5880-5883.1987

Mutational analysis of the lambda int gene: DNA sequence of dominant mutations.

S. E. Bear, J. B. Clemens, L. W. Enquist, R. J. Zagursky

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

We have combined techniques of genetic and physical mapping with rapid DNA sequence analysis to identify the nucleotide change in lambda int mutations. These mutations define two dominant phenotypic classes: (i) recombination that is partially independent of accessory factors, and (ii) inhibition of wild-type Int by missense or nonsense proteins, i.e., negative complementation.

Original language	English (US)
Pages (from-to)	5880-5883
Number of pages	4
Journal	Journal of bacteriology
Volume	169
Issue number	12
DOIs	https://doi.org/10.1128/jb.169.12.5880-5883.1987
State	Published - Dec 1987

All Science Journal Classification (ASJC) codes

Microbiology
Molecular Biology

Access to Document

10.1128/jb.169.12.5880-5883.1987

Cite this

@article{eaeea15c2281445b89747d136ed1e19a,

title = "Mutational analysis of the lambda int gene: DNA sequence of dominant mutations.",

abstract = "We have combined techniques of genetic and physical mapping with rapid DNA sequence analysis to identify the nucleotide change in lambda int mutations. These mutations define two dominant phenotypic classes: (i) recombination that is partially independent of accessory factors, and (ii) inhibition of wild-type Int by missense or nonsense proteins, i.e., negative complementation.",

author = "Bear, {S. E.} and Clemens, {J. B.} and Enquist, {L. W.} and Zagursky, {R. J.}",

year = "1987",

month = dec,

doi = "10.1128/jb.169.12.5880-5883.1987",

language = "English (US)",

volume = "169",

pages = "5880--5883",

journal = "Journal of bacteriology",

issn = "0021-9193",

publisher = "American Society for Microbiology",

number = "12",

}

TY - JOUR

T1 - Mutational analysis of the lambda int gene

T2 - DNA sequence of dominant mutations.

AU - Bear, S. E.

AU - Clemens, J. B.

AU - Enquist, L. W.

AU - Zagursky, R. J.

PY - 1987/12

Y1 - 1987/12

N2 - We have combined techniques of genetic and physical mapping with rapid DNA sequence analysis to identify the nucleotide change in lambda int mutations. These mutations define two dominant phenotypic classes: (i) recombination that is partially independent of accessory factors, and (ii) inhibition of wild-type Int by missense or nonsense proteins, i.e., negative complementation.

AB - We have combined techniques of genetic and physical mapping with rapid DNA sequence analysis to identify the nucleotide change in lambda int mutations. These mutations define two dominant phenotypic classes: (i) recombination that is partially independent of accessory factors, and (ii) inhibition of wild-type Int by missense or nonsense proteins, i.e., negative complementation.

UR - http://www.scopus.com/inward/record.url?scp=0023478505&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023478505&partnerID=8YFLogxK

U2 - 10.1128/jb.169.12.5880-5883.1987

DO - 10.1128/jb.169.12.5880-5883.1987

M3 - Article

C2 - 2960665

AN - SCOPUS:0023478505

SN - 0021-9193

VL - 169

SP - 5880

EP - 5883

JO - Journal of bacteriology

JF - Journal of bacteriology

IS - 12

ER -

Mutational analysis of the lambda int gene: DNA sequence of dominant mutations.

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this