Molecular mechanisms of protein-mediated membrane fusion

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43 Scopus citations


Two recent X-ray structures shed new light on the molecular mechanisms by which viral proteins mediate membrane fusion. In both cases it is clear that the fusion proteins are capable of dramatic conformational rearrangements. Studies of the intracellular fusion machinery used in vesicular transport have also advanced rapidly, although high-resolution structural information is not yet available.

Original languageEnglish (US)
Pages (from-to)507-513
Number of pages7
JournalCurrent Opinion in Structural Biology
Issue number4
StatePublished - Aug 1995

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Structural Biology


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