Modeling canine rabies virus transmission dynamics

Malavika Rajeev; C. Jessica E. Metcalf; Katie Hampson

doi:10.1016/B978-0-12-818705-0.00020-0

Modeling canine rabies virus transmission dynamics

Malavika Rajeev, C. Jessica E. Metcalf, Katie Hampson

Research output: Chapter in Book/Report/Conference proceeding › Chapter

5 Scopus citations

Abstract

Mathematical models of infectious disease are used to develop an understanding of disease dynamics and aid in designing control strategies. Modeling can also shed light on how dynamics, and therefore intervention strategies, may change as control is implemented. In light of the mounting evidence that elimination of canine rabies is a realistic objective, the WHO has set a global target of zero human deaths due to dog-mediated rabies by 2030. In this chapter, we focus on how dynamic epidemiological modeling can guide efforts to achieve this goal. We review existing modeling work and identify insights generated, outstanding questions, and gaps in our knowledge. We further discuss the role that modeling can play in the future to inform elimination.

Original language	English (US)
Title of host publication	Rabies
Subtitle of host publication	Scientific Basis of the Disease and Its Management, Fourth Edition
Publisher	Elsevier
Pages	655-670
Number of pages	16
ISBN (Electronic)	9780128187050
ISBN (Print)	9780128205723
DOIs	https://doi.org/10.1016/B978-0-12-818705-0.00020-0
State	Published - Jan 1 2020

All Science Journal Classification (ASJC) codes

General Medicine

Keywords

Canine rabies
Disease modeling
Mass dog vaccination
Transmission dynamics
Zero by 30

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10.1016/B978-0-12-818705-0.00020-0

Cite this

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AU - Metcalf, C. Jessica E.

AU - Hampson, Katie

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AB - Mathematical models of infectious disease are used to develop an understanding of disease dynamics and aid in designing control strategies. Modeling can also shed light on how dynamics, and therefore intervention strategies, may change as control is implemented. In light of the mounting evidence that elimination of canine rabies is a realistic objective, the WHO has set a global target of zero human deaths due to dog-mediated rabies by 2030. In this chapter, we focus on how dynamic epidemiological modeling can guide efforts to achieve this goal. We review existing modeling work and identify insights generated, outstanding questions, and gaps in our knowledge. We further discuss the role that modeling can play in the future to inform elimination.

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KW - Disease modeling

KW - Mass dog vaccination

KW - Transmission dynamics

KW - Zero by 30

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M3 - Chapter

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ER -

Modeling canine rabies virus transmission dynamics

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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