Model-free analysis of time-dependent single-molecule spectroscopy: Dynamics of biological macromolecules

Kevin Welsher, Haw Yang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Rigorous and unbiased statistical analysis of singlemolecule data is now recognized as a crucial component to substantiate any discovery made through such experiments. This presentation summarizes many such tools, and ventures some future directions in the context of the dynamics of biological macromolecules.

Original languageEnglish (US)
Title of host publication2012 9th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI 2012 - Proceedings
Pages921-923
Number of pages3
DOIs
StatePublished - Aug 15 2012
Event2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012 - Barcelona, Spain
Duration: May 2 2012May 5 2012

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Other

Other2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012
CountrySpain
CityBarcelona
Period5/2/125/5/12

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Keywords

  • Fisher information
  • change point
  • maximum entropy
  • maximum information
  • protein dyamics
  • single-molecule FRET

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    Welsher, K., & Yang, H. (2012). Model-free analysis of time-dependent single-molecule spectroscopy: Dynamics of biological macromolecules. In 2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012 - Proceedings (pp. 921-923). [6235705] (Proceedings - International Symposium on Biomedical Imaging). https://doi.org/10.1109/ISBI.2012.6235705