Model for transition from waves to synchrony in the olfactory lobe of Limax

Bard Ermentrout, Jing W. Wang, Jorge Flores, Alan Gelperin

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25 Scopus citations


A biophysical model for the interactions between bursting (B) cells and nonbursting (NB) cells in the procerebral lobe of Limax is developed and tested. Phase-sensitivity of the NB cells is exhibited due to the strong inhibition from the rhythmically bursting B cells. Electrical and chemical junctions coupled with a parameter gradient lead to sustained periodic waves in the lobe. Excitatory interactions between the NB cells, which rarely fire, lead to stimulus evoked synchrony in the lobe oscillations. A novel calcium current is suggested to explain the effects of nitric oxide (NO) on the lobe. Gap junctions are shown both experimentally and through simulations to be required for the oscillating field potentials.

Original languageEnglish (US)
Pages (from-to)365-383
Number of pages19
JournalJournal of Computational Neuroscience
Issue number3
StatePublished - 2004

All Science Journal Classification (ASJC) codes

  • Sensory Systems
  • Cellular and Molecular Neuroscience
  • Cognitive Neuroscience


  • Gap junctions
  • Limax
  • Nitric oxide
  • Olfaction
  • Oscillations
  • Waves


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