Mitosis: New Roles for Myosin-X and Actin at the Spindle

Martin Wühr, Timothy J. Mitchison, Christine M. Field

Research output: Contribution to journalShort survey

12 Scopus citations

Abstract

Roles for actin and myosin in positioning mitotic spindles in the cell are well established. A recent study of myosin-X function in early Xenopus embryo mitosis now reports that this unconventional myosin is required for pole integrity and normal spindle length by localizing to poles and exerting pulling forces on actin filaments within the spindle.

Original languageEnglish (US)
Pages (from-to)R912-R914
JournalCurrent Biology
Volume18
Issue number19
DOIs
StatePublished - Oct 14 2008
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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