Mitosis: New Roles for Myosin-X and Actin at the Spindle

Martin Wühr; Timothy J. Mitchison; Christine M. Field

doi:10.1016/j.cub.2008.08.043

Mitosis: New Roles for Myosin-X and Actin at the Spindle

Martin Wühr, Timothy J. Mitchison, Christine M. Field

Research output: Contribution to journal › Short survey › peer-review

14 Scopus citations

Abstract

Roles for actin and myosin in positioning mitotic spindles in the cell are well established. A recent study of myosin-X function in early Xenopus embryo mitosis now reports that this unconventional myosin is required for pole integrity and normal spindle length by localizing to poles and exerting pulling forces on actin filaments within the spindle.

Original language	English (US)
Pages (from-to)	R912-R914
Journal	Current Biology
Volume	18
Issue number	19
DOIs	https://doi.org/10.1016/j.cub.2008.08.043
State	Published - Oct 14 2008
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

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10.1016/j.cub.2008.08.043

Cite this

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title = "Mitosis: New Roles for Myosin-X and Actin at the Spindle",

abstract = "Roles for actin and myosin in positioning mitotic spindles in the cell are well established. A recent study of myosin-X function in early Xenopus embryo mitosis now reports that this unconventional myosin is required for pole integrity and normal spindle length by localizing to poles and exerting pulling forces on actin filaments within the spindle.",

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AU - Wühr, Martin

AU - Mitchison, Timothy J.

AU - Field, Christine M.

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Y1 - 2008/10/14

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AB - Roles for actin and myosin in positioning mitotic spindles in the cell are well established. A recent study of myosin-X function in early Xenopus embryo mitosis now reports that this unconventional myosin is required for pole integrity and normal spindle length by localizing to poles and exerting pulling forces on actin filaments within the spindle.

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Mitosis: New Roles for Myosin-X and Actin at the Spindle

Abstract

All Science Journal Classification (ASJC) codes

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