Mid-infrared (λ = 8.4-9.9 μm) light scattering from porcine tissue

Sabbir Liakat; Anna P.M. Michel; Kevin A. Bors; Claire F. Gmachl

doi:10.1063/1.4748331

Mid-infrared (λ = 8.4-9.9 μm) light scattering from porcine tissue

Sabbir Liakat, Anna P.M. Michel, Kevin A. Bors, Claire F. Gmachl

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Back-scattering of mid-infrared light from porcine skin is studied versus wavelength and angle for a Quantum Cascade laser and a broadband infrared light source. Scattering is detected over 30° away from the specular angle for both sources, and modulation patterns with angle are seen when using the laser. A nonlinear increase in scattered light intensity versus input power indicates that directional scattering from within the skin is dominant. Collagen fibers in the dermis layer, over 200 μm deep into the skin, are conducive to such scattering. We conclude that mid-infrared light penetrates deep enough for potential glucose detection in dermal interstitial fluid.

Original language	English (US)
Article number	093705
Journal	Applied Physics Letters
Volume	101
Issue number	9
DOIs	https://doi.org/10.1063/1.4748331
State	Published - Aug 27 2012

All Science Journal Classification (ASJC) codes

Physics and Astronomy (miscellaneous)

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10.1063/1.4748331

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title = "Mid-infrared (λ = 8.4-9.9 μm) light scattering from porcine tissue",

abstract = "Back-scattering of mid-infrared light from porcine skin is studied versus wavelength and angle for a Quantum Cascade laser and a broadband infrared light source. Scattering is detected over 30° away from the specular angle for both sources, and modulation patterns with angle are seen when using the laser. A nonlinear increase in scattered light intensity versus input power indicates that directional scattering from within the skin is dominant. Collagen fibers in the dermis layer, over 200 μm deep into the skin, are conducive to such scattering. We conclude that mid-infrared light penetrates deep enough for potential glucose detection in dermal interstitial fluid.",

author = "Sabbir Liakat and Michel, {Anna P.M.} and Bors, {Kevin A.} and Gmachl, {Claire F.}",

note = "Funding Information: The authors thank the Wendy and Eric Schmidt Foundation, the National Science Foundation under Grant (No. EEC-0540832), and the PEI/Grand Challenges Program. ",

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T1 - Mid-infrared (λ = 8.4-9.9 μm) light scattering from porcine tissue

AU - Liakat, Sabbir

AU - Michel, Anna P.M.

AU - Bors, Kevin A.

AU - Gmachl, Claire F.

N1 - Funding Information: The authors thank the Wendy and Eric Schmidt Foundation, the National Science Foundation under Grant (No. EEC-0540832), and the PEI/Grand Challenges Program.

PY - 2012/8/27

Y1 - 2012/8/27

N2 - Back-scattering of mid-infrared light from porcine skin is studied versus wavelength and angle for a Quantum Cascade laser and a broadband infrared light source. Scattering is detected over 30° away from the specular angle for both sources, and modulation patterns with angle are seen when using the laser. A nonlinear increase in scattered light intensity versus input power indicates that directional scattering from within the skin is dominant. Collagen fibers in the dermis layer, over 200 μm deep into the skin, are conducive to such scattering. We conclude that mid-infrared light penetrates deep enough for potential glucose detection in dermal interstitial fluid.

AB - Back-scattering of mid-infrared light from porcine skin is studied versus wavelength and angle for a Quantum Cascade laser and a broadband infrared light source. Scattering is detected over 30° away from the specular angle for both sources, and modulation patterns with angle are seen when using the laser. A nonlinear increase in scattered light intensity versus input power indicates that directional scattering from within the skin is dominant. Collagen fibers in the dermis layer, over 200 μm deep into the skin, are conducive to such scattering. We conclude that mid-infrared light penetrates deep enough for potential glucose detection in dermal interstitial fluid.

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Mid-infrared (λ = 8.4-9.9 μm) light scattering from porcine tissue

Abstract

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