Microstructured extracellular matrices in tissue engineering and development: An update

Joe Tien; Celeste M. Nelson

doi:10.1007/s10439-013-0912-5

Microstructured extracellular matrices in tissue engineering and development: An update

Joe Tien, Celeste M. Nelson

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Microstructured extracellular matrix (ECM), which contains heterogeneous features of the same size scale (5-100 μm) as tissue organoids, has become an important material for the engineering of functional tissues and for the study of tissue-level biology. This review describes methods to generate this class of ECM, and highlights recent advances in the application of microstructured ECM to problems in basic and applied biology. It also discusses computational techniques to analyze and optimize the microstructural patterns for a desired functional output.

Original language	English (US)
Pages (from-to)	1413-1423
Number of pages	11
Journal	Annals of Biomedical Engineering
Volume	42
Issue number	7
DOIs	https://doi.org/10.1007/s10439-013-0912-5
State	Published - Jul 2014

All Science Journal Classification (ASJC) codes

Biomedical Engineering

Keywords

Bio-inspired design
Biomimicry
Micropatterning
Multi-scale biomaterials
Soft lithography

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10.1007/s10439-013-0912-5

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KW - Multi-scale biomaterials

KW - Soft lithography

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Microstructured extracellular matrices in tissue engineering and development: An update

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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