Microplate evaluation of process adsorbents

Christopher J. Welch; Mohamed Shaimi; Mirlinda Biba; Jennifer R. Chilenski; Ronald H. Szumigala; Ulf Dolling; David J. Mathre; Paul J. Reider

doi:10.1002/1615-9314(20020901)25:13<847::AID-JSSC847>3.0.CO;2-2

Microplate evaluation of process adsorbents

Christopher J. Welch, Mohamed Shaimi, Mirlinda Biba, Jennifer R. Chilenski, Ronald H. Szumigala, Ulf Dolling, David J. Mathre, Paul J. Reider

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

A microplate-based assay to rapidly identify adsorbents suitable for removing process impurities is described. A solution containing both product and impurity is added to a number of wells, each containing a small amount of a candidate adsorbent. After equilibration, analysis of the supernatant solution allows one to determine the extent of adsorption of both product and impurity. Fast analysis techniques such as flow injection analysis LC-MS or the use of colorimetric indicators allows rapid identification of the most selective adsorbents for a given separation problem.

Original language	English (US)
Pages (from-to)	847-850
Number of pages	4
Journal	Journal of Separation Science
Volume	25
Issue number	13
DOIs	https://doi.org/10.1002/1615-9314(20020901)25:13<847::AID-JSSC847>3.0.CO;2-2
State	Published - Sep 2002
Externally published	Yes

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Filtration and Separation

Keywords

Batch adsorption
High-throughput screening
LC-MS
Process adsorbents

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10.1002/1615-9314(20020901)25:13<847::AID-JSSC847>3.0.CO;2-2

Cite this

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title = "Microplate evaluation of process adsorbents",

abstract = "A microplate-based assay to rapidly identify adsorbents suitable for removing process impurities is described. A solution containing both product and impurity is added to a number of wells, each containing a small amount of a candidate adsorbent. After equilibration, analysis of the supernatant solution allows one to determine the extent of adsorption of both product and impurity. Fast analysis techniques such as flow injection analysis LC-MS or the use of colorimetric indicators allows rapid identification of the most selective adsorbents for a given separation problem.",

keywords = "Batch adsorption, High-throughput screening, LC-MS, Process adsorbents",

author = "Welch, {Christopher J.} and Mohamed Shaimi and Mirlinda Biba and Chilenski, {Jennifer R.} and Szumigala, {Ronald H.} and Ulf Dolling and Mathre, {David J.} and Reider, {Paul J.}",

year = "2002",

month = sep,

doi = "10.1002/1615-9314(20020901)25:13<847::AID-JSSC847>3.0.CO;2-2",

language = "English (US)",

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pages = "847--850",

journal = "Journal of Separation Science",

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TY - JOUR

T1 - Microplate evaluation of process adsorbents

AU - Welch, Christopher J.

AU - Shaimi, Mohamed

AU - Biba, Mirlinda

AU - Chilenski, Jennifer R.

AU - Szumigala, Ronald H.

AU - Dolling, Ulf

AU - Mathre, David J.

AU - Reider, Paul J.

PY - 2002/9

Y1 - 2002/9

N2 - A microplate-based assay to rapidly identify adsorbents suitable for removing process impurities is described. A solution containing both product and impurity is added to a number of wells, each containing a small amount of a candidate adsorbent. After equilibration, analysis of the supernatant solution allows one to determine the extent of adsorption of both product and impurity. Fast analysis techniques such as flow injection analysis LC-MS or the use of colorimetric indicators allows rapid identification of the most selective adsorbents for a given separation problem.

AB - A microplate-based assay to rapidly identify adsorbents suitable for removing process impurities is described. A solution containing both product and impurity is added to a number of wells, each containing a small amount of a candidate adsorbent. After equilibration, analysis of the supernatant solution allows one to determine the extent of adsorption of both product and impurity. Fast analysis techniques such as flow injection analysis LC-MS or the use of colorimetric indicators allows rapid identification of the most selective adsorbents for a given separation problem.

KW - Batch adsorption

KW - High-throughput screening

KW - LC-MS

KW - Process adsorbents

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DO - 10.1002/1615-9314(20020901)25:13<847::AID-JSSC847>3.0.CO;2-2

M3 - Article

AN - SCOPUS:0036750567

SN - 1615-9306

VL - 25

SP - 847

EP - 850

JO - Journal of Separation Science

JF - Journal of Separation Science

IS - 13

ER -

Microplate evaluation of process adsorbents

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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