Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

Alireza Abbaspourrad; Wynter J. Duncanson; Natalia Lebedeva; Shin Hyun Kim; Aleksandr P. Zhushma; Sujit S. Datta; Paul A. Dayton; Sergei S. Sheiko; Michael Rubinstein; David A. Weitz

doi:10.1021/la402598p

Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

Alireza Abbaspourrad
, Wynter J. Duncanson
, Natalia Lebedeva
, Shin Hyun Kim
, Aleksandr P. Zhushma
, Sujit S. Datta
, Paul A. Dayton
, Sergei S. Sheiko
, Michael Rubinstein
, David A. Weitz

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.

Original language	English (US)
Pages (from-to)	12352-12357
Number of pages	6
Journal	Langmuir
Volume	29
Issue number	40
DOIs	https://doi.org/10.1021/la402598p
State	Published - Oct 8 2013
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Materials Science
Condensed Matter Physics
Surfaces and Interfaces
Spectroscopy
Electrochemistry

Access to Document

10.1021/la402598p

Cite this

@article{29f8f28dbcb54c32894908eb8660f106,

title = "Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement",

abstract = "We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.",

author = "Alireza Abbaspourrad and Duncanson, \{Wynter J.\} and Natalia Lebedeva and Kim, \{Shin Hyun\} and Zhushma, \{Aleksandr P.\} and Datta, \{Sujit S.\} and Dayton, \{Paul A.\} and Sheiko, \{Sergei S.\} and Michael Rubinstein and Weitz, \{David A.\}",

year = "2013",

month = oct,

day = "8",

doi = "10.1021/la402598p",

language = "English (US)",

volume = "29",

pages = "12352--12357",

journal = "Langmuir",

issn = "0743-7463",

publisher = "American Chemical Society",

number = "40",

}

TY - JOUR

T1 - Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

AU - Abbaspourrad, Alireza

AU - Duncanson, Wynter J.

AU - Lebedeva, Natalia

AU - Kim, Shin Hyun

AU - Zhushma, Aleksandr P.

AU - Datta, Sujit S.

AU - Dayton, Paul A.

AU - Sheiko, Sergei S.

AU - Rubinstein, Michael

AU - Weitz, David A.

PY - 2013/10/8

Y1 - 2013/10/8

N2 - We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.

AB - We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.

UR - https://www.scopus.com/pages/publications/84885405198

UR - https://www.scopus.com/pages/publications/84885405198#tab=citedBy

U2 - 10.1021/la402598p

DO - 10.1021/la402598p

M3 - Article

C2 - 24066971

AN - SCOPUS:84885405198

SN - 0743-7463

VL - 29

SP - 12352

EP - 12357

JO - Langmuir

JF - Langmuir

IS - 40

ER -

Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this