Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

Alireza Abbaspourrad; Wynter J. Duncanson; Natalia Lebedeva; Shin Hyun Kim; Aleksandr P. Zhushma; Sujit S. Datta; Paul A. Dayton; Sergei S. Sheiko; Michael Rubinstein; David A. Weitz

doi:10.1021/la402598p

Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

Alireza Abbaspourrad, Wynter J. Duncanson, Natalia Lebedeva, Shin Hyun Kim, Aleksandr P. Zhushma, Sujit S. Datta, Paul A. Dayton, Sergei S. Sheiko, Michael Rubinstein, David A. Weitz

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.

Original language	English (US)
Pages (from-to)	12352-12357
Number of pages	6
Journal	Langmuir
Volume	29
Issue number	40
DOIs	https://doi.org/10.1021/la402598p
State	Published - Oct 8 2013
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Materials Science
Condensed Matter Physics
Surfaces and Interfaces
Spectroscopy
Electrochemistry

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10.1021/la402598p

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title = "Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement",

abstract = "We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.",

author = "Alireza Abbaspourrad and Duncanson, {Wynter J.} and Natalia Lebedeva and Kim, {Shin Hyun} and Zhushma, {Aleksandr P.} and Datta, {Sujit S.} and Dayton, {Paul A.} and Sheiko, {Sergei S.} and Michael Rubinstein and Weitz, {David A.}",

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doi = "10.1021/la402598p",

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T1 - Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

AU - Abbaspourrad, Alireza

AU - Duncanson, Wynter J.

AU - Lebedeva, Natalia

AU - Kim, Shin Hyun

AU - Zhushma, Aleksandr P.

AU - Datta, Sujit S.

AU - Dayton, Paul A.

AU - Sheiko, Sergei S.

AU - Rubinstein, Michael

AU - Weitz, David A.

PY - 2013/10/8

Y1 - 2013/10/8

N2 - We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.

AB - We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.

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JO - Langmuir

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Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

Abstract

All Science Journal Classification (ASJC) codes

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