Microfluidic fabrication of stable gas-filled microcapsules for acoustic contrast enhancement

Alireza Abbaspourrad, Wynter J. Duncanson, Natalia Lebedeva, Shin Hyun Kim, Aleksandr P. Zhushma, Sujit S. Datta, Paul A. Dayton, Sergei S. Sheiko, Michael Rubinstein, David A. Weitz

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


We introduce a facile approach for the production of gas-filled microcapsules designed to withstand high pressures. We exploit microfluidics to fabricate water-filled microcapsules that are then externally triggered to become gas-filled, thus making them more echogenic. In addition, the gas-filled microcapsules have a solid polymer shell making them resistant to pressure-induced buckling, which makes them more mechanically robust than traditional prestabilized microbubbles; this should increase the potential of their utility for acoustic imaging of porous media with high hydrostatic pressures such as oil reservoirs.

Original languageEnglish (US)
Pages (from-to)12352-12357
Number of pages6
Issue number40
StatePublished - Oct 8 2013
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Materials Science
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Spectroscopy
  • Electrochemistry


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