Microbial metabolite as icebreaker for immunotherapy

Yong Tang, Yibin Kang

Research output: Contribution to journalComment/debatepeer-review

3 Scopus citations


Immunotherapy has limited success in triple-negative breast cancer (TNBC). In this issue of Cell Metabolism, Wang et al. found that microbial metabolite TMAO boosts CD8+ T cell-mediated antitumor immunity by inducing pyroptosis in tumor cells, enhancing the efficacy of immunotherapy in TNBC (Wang et al., 2022).

Original languageEnglish (US)
Pages (from-to)506-507
Number of pages2
JournalCell Metabolism
Issue number4
StatePublished - Apr 5 2022

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Physiology
  • Cell Biology


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