Michael additions of 3,3-dimethylacrylamides and amines: Synthesis of the growth hormone secretagogue L-692,585

Kenneth M. Wells; Kai Rossen; David Askin; Frederick W. Hartner; R. P. Volante; Paul J. Reider

doi:10.1080/00397919508015901

Michael additions of 3,3-dimethylacrylamides and amines: Synthesis of the growth hormone secretagogue L-692,585

Kenneth M. Wells, Kai Rossen, David Askin, Frederick W. Hartner, R. P. Volante, Paul J. Reider

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A highly efficient synthesis of the potent Human Growth Hormone Secretagogue L-692,585 1 via a Micheal addition with a 3,3-dimethyl acrylic acid derivative 7 and (R)-1-amino-2-propanol 2 is presented.

Original language	English (US)
Pages (from-to)	2197-2202
Number of pages	6
Journal	Synthetic Communications
Volume	25
Issue number	14
DOIs	https://doi.org/10.1080/00397919508015901
State	Published - Jul 1 1995
Externally published	Yes

All Science Journal Classification (ASJC) codes

Organic Chemistry

Access to Document

10.1080/00397919508015901

Cite this

@article{6365da45d05a4242abafbc22524e5c18,

title = "Michael additions of 3,3-dimethylacrylamides and amines: Synthesis of the growth hormone secretagogue L-692,585",

abstract = "A highly efficient synthesis of the potent Human Growth Hormone Secretagogue L-692,585 1 via a Micheal addition with a 3,3-dimethyl acrylic acid derivative 7 and (R)-1-amino-2-propanol 2 is presented.",

author = "Wells, \{Kenneth M.\} and Kai Rossen and David Askin and Hartner, \{Frederick W.\} and Volante, \{R. P.\} and Reider, \{Paul J.\}",

year = "1995",

month = jul,

day = "1",

doi = "10.1080/00397919508015901",

language = "English (US)",

volume = "25",

pages = "2197--2202",

journal = "Synthetic Communications",

issn = "0039-7911",

publisher = "Taylor and Francis Ltd.",

number = "14",

}

TY - JOUR

T1 - Michael additions of 3,3-dimethylacrylamides and amines

T2 - Synthesis of the growth hormone secretagogue L-692,585

AU - Wells, Kenneth M.

AU - Rossen, Kai

AU - Askin, David

AU - Hartner, Frederick W.

AU - Volante, R. P.

AU - Reider, Paul J.

PY - 1995/7/1

Y1 - 1995/7/1

N2 - A highly efficient synthesis of the potent Human Growth Hormone Secretagogue L-692,585 1 via a Micheal addition with a 3,3-dimethyl acrylic acid derivative 7 and (R)-1-amino-2-propanol 2 is presented.

AB - A highly efficient synthesis of the potent Human Growth Hormone Secretagogue L-692,585 1 via a Micheal addition with a 3,3-dimethyl acrylic acid derivative 7 and (R)-1-amino-2-propanol 2 is presented.

UR - https://www.scopus.com/pages/publications/0029013912

UR - https://www.scopus.com/inward/citedby.url?scp=0029013912&partnerID=8YFLogxK

U2 - 10.1080/00397919508015901

DO - 10.1080/00397919508015901

M3 - Article

AN - SCOPUS:0029013912

SN - 0039-7911

VL - 25

SP - 2197

EP - 2202

JO - Synthetic Communications

JF - Synthetic Communications

IS - 14

ER -

Michael additions of 3,3-dimethylacrylamides and amines: Synthesis of the growth hormone secretagogue L-692,585

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this