Michael additions of 3,3-dimethylacrylamides and amines: Synthesis of the growth hormone secretagogue L-692,585

Kenneth M. Wells, Kai Rossen, David Askin, Frederick W. Hartner, R. P. Volante, Paul J. Reider

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

A highly efficient synthesis of the potent Human Growth Hormone Secretagogue L-692,585 1 via a Micheal addition with a 3,3-dimethyl acrylic acid derivative 7 and (R)-1-amino-2-propanol 2 is presented.

Original languageEnglish (US)
Pages (from-to)2197-2202
Number of pages6
JournalSynthetic Communications
Volume25
Issue number14
DOIs
StatePublished - Jul 1 1995
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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