Mechanistic Investigations of the Asymmetric Hydrogenation of Enamides with Neutral Bis(phosphine) Cobalt Precatalysts

Medicine & Life Sciences

• acrylic acid 10%
• Alkanes 11%
• Benzene 9%
• Cobalt 70%
• Density Functional Theory 12%
• Deuterium 10%
• Electron Spin Resonance Spectroscopy 9%
• Electrons 5%
• Hydrogenation 97%
• Isotopes 7%
• Kinetics 10%
• Ligands 5%
• Methanol 7%
• N-acetyldehydroalanine methyl ester 18%
• Oxidation-Reduction 7%
• phosphine 100%
• Spectrum Analysis 57%
• X-Ray Diffraction 8%

Engineering & Materials Science

• Benzene 8%
• Catalysts 6%
• Cobalt 67%
• Density functional theory 10%
• Deuterium 10%
• Electrons 7%
• Experiments 2%
• Hydrogenation 73%
• Isotopes 9%
• Labeling 14%
• Ligands 9%
• Methanol 7%
• Monitoring 4%
• Oxidation-Reduction 9%
• Paraffins 8%
• Paramagnetic resonance 9%
• Spectroscopy 65%
• X ray diffraction 7%

Chemical Compounds

• Acrylate 5%
• Benzene 4%
• Catalysis 3%
• Catalyst 2%
• Density Functional Theory 3%
• Diastereomer 5%
• Enamide 78%
• EPR Spectroscopy 5%
• Hydrogenation 43%
• Kinetic Isotope Effect 6%
• Ligand 2%
• Methanol 3%
• Phosphine 52%
• Resonance 32%
• Spectroscopy 26%
• Time 2%
• Ultraviolet Spectrum 4%
• X-Ray Diffraction 2%