Macrophages in the Mammary Gland Stem Cell Niche: A Double-Edged Sword in Tissue Regeneration and Tumor Initiation

Keyphrases

• Mammary Gland 100%
• Tumor Initiation 100%
• Macrophages 100%
• Double-edged Sword 100%
• Stem Cell Niche 100%
• Tissue Regeneration 100%
• Tissue-resident Macrophages 100%
• C-X-C Chemokine Receptor Type 4 (CXCR4) 60%
• Tumor-initiating Cells 40%
• Hijack 20%
• Mammary Stem Cells 20%
• Cell-intrinsic 20%
• In Cancer 20%
• Immune Evasion 20%
• Tumorigenesis 20%
• Vulnerability 20%
• Circuitry 20%
• Self-renewal 20%
• Tumor Immunity 20%
• Malignancy 20%
• Stem Cell Population 20%
• Cancer Development 20%
• Tumor Development 20%
• Malignant Progression 20%
• Tumor Stage 20%
• Retinoic Acid 20%
• Regenerative Potential 20%
• Acid Production 20%
• Regulatory T Cells 20%
• Cell Maintenance 20%
• Self-regeneration 20%
• Cellular Niche 20%
• Tumor Control 20%
• Immunosuppressive Microenvironment 20%
• Cancer Hallmarks 20%
• ALDH1A2 20%
• Beta-catenin 20%
• Chemokine Ligand 12 (CXCL12) 20%
• Therapeutic Window 20%
• CXCR4 Signaling 20%
• Cancer-associated Fibroblasts 20%
• Immune Therapy 20%
• CXCL12-CXCR4 20%
• Developmental Niche 20%

Biochemistry, Genetics and Molecular Biology

• Stem Cell 100%
• Tumor Initiation 100%
• Macrophage 100%
• Tissue Regeneration 100%
• CXCR4 83%
• Cancer Stem Cell 33%
• Carcinogenesis 16%
• Catenin 16%
• Protein Kinase B 16%
• Immune Evasion 16%
• Tretinoin 16%
• Retinoic Acid 16%
• Regulatory T Cell 16%
• Tumor Immunity 16%
• Fibroblast 16%
• ALDH1A2 16%

Immunology and Microbiology

• Macrophage 100%
• Stem Cell Niche 100%
• Tissue Regeneration 100%
• Mammary Gland 100%
• CXCR4 83%
• Cancer Stem Cell 33%
• Stem Cell 33%
• Cell Population 16%
• Catenin 16%
• Immune Evasion 16%
• Tumor Immunity 16%
• Immunosuppressive Drug 16%
• Regulatory T Cell 16%
• Malignant Progression 16%
• Fibroblast 16%