Low-Dimensional Spatiotemporal Dynamics Underlie Cortex-wide Neural Activity

Camden J. MacDowell; Timothy J. Buschman

doi:10.1016/j.cub.2020.04.090

Low-Dimensional Spatiotemporal Dynamics Underlie Cortex-wide Neural Activity

Camden J. MacDowell, Timothy J. Buschman

Research output: Contribution to journal › Article › peer-review

54 Scopus citations

Abstract

Behaviors arise from the flow of neural activity through the brain. MacDowell and Buschman show cortex-wide neural activity, in mice, can be explained by a set of 14 motifs, each capturing a unique spatiotemporal pattern of neural activity. Motifs generalized across animals and behaviors, suggesting that they capture core patterns of cortical activity.

Original language	English (US)
Pages (from-to)	2665-2680.e8
Journal	Current Biology
Volume	30
Issue number	14
DOIs	https://doi.org/10.1016/j.cub.2020.04.090
State	Published - Jul 20 2020

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology
General Agricultural and Biological Sciences

Keywords

calcium imaging
cognitive control
dimensionality of neural activity
mesoscale imaging
mouse
neural dynamics

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10.1016/j.cub.2020.04.090

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abstract = "Behaviors arise from the flow of neural activity through the brain. MacDowell and Buschman show cortex-wide neural activity, in mice, can be explained by a set of 14 motifs, each capturing a unique spatiotemporal pattern of neural activity. Motifs generalized across animals and behaviors, suggesting that they capture core patterns of cortical activity.",

keywords = "calcium imaging, cognitive control, dimensionality of neural activity, mesoscale imaging, mouse, neural dynamics",

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AB - Behaviors arise from the flow of neural activity through the brain. MacDowell and Buschman show cortex-wide neural activity, in mice, can be explained by a set of 14 motifs, each capturing a unique spatiotemporal pattern of neural activity. Motifs generalized across animals and behaviors, suggesting that they capture core patterns of cortical activity.

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KW - mesoscale imaging

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KW - neural dynamics

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Low-Dimensional Spatiotemporal Dynamics Underlie Cortex-wide Neural Activity

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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