Liver Metastatic Breast Cancer: Epidemiology, Dietary Interventions, and Related Metabolism

Qianying Zuo, Nicole Hwajin Park, Jenna Kathryn Lee, Zeynep Madak Erdogan

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


The median overall survival of patients with metastatic breast cancer is only 2–3 years, and for patients with untreated liver metastasis, it is as short as 4–8 months. Improving the survival of women with breast cancer requires more effective anti-cancer strategies, especially for metastatic disease. Nutrients can influence tumor microenvironments, and cancer metabolism can be manipulated via a dietary modification to enhance anti-cancer strategies. Yet, there are no standard evidence-based recommendations for diet therapies before or during cancer treatment, and few studies provide definitive data that certain diets can mediate tumor progression or therapeutic effectiveness in human cancer. This review focuses on metastatic breast cancer, in particular liver metastatic forms, and recent studies on the impact of diets on disease progression and treatment.

Original languageEnglish (US)
Article number2376
Issue number12
StatePublished - Jun 1 2022
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Food Science
  • Nutrition and Dietetics


  • breast cancer liver metastasis
  • fasting-mimicking diet
  • western diet


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