TY - JOUR
T1 - Linkage between vitamin D-binding protein and α-fetoprotein in the mouse
AU - Guan, X. J.
AU - Arhin, G.
AU - Leung, J.
AU - Tilghman, S. M.
PY - 1996
Y1 - 1996
N2 - The albumin gene family consists of four evolutionarily related genes that code for serum transport proteins. In rodents, the genes for albumin, α-fetoprotein, and αtALB are physically linked within 100 kilobases of DNA. The fourth gene, Gc, encoding vitamin D-binding protein or group-specific component, maps to the same chromosome as the other family members, but linkage has not been established. This report describes the genetic and physical mapping of Gc in mouse and establishes that, although Gc is genetically linked to the other genes, its physical distance from them extends beyond the resolution range of yeast artificial chromosome cloning and pulsed-field gel electrophoresis.
AB - The albumin gene family consists of four evolutionarily related genes that code for serum transport proteins. In rodents, the genes for albumin, α-fetoprotein, and αtALB are physically linked within 100 kilobases of DNA. The fourth gene, Gc, encoding vitamin D-binding protein or group-specific component, maps to the same chromosome as the other family members, but linkage has not been established. This report describes the genetic and physical mapping of Gc in mouse and establishes that, although Gc is genetically linked to the other genes, its physical distance from them extends beyond the resolution range of yeast artificial chromosome cloning and pulsed-field gel electrophoresis.
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U2 - 10.1007/s003359900028
DO - 10.1007/s003359900028
M3 - Article
C2 - 8835525
AN - SCOPUS:0030074264
SN - 0938-8990
VL - 7
SP - 103
EP - 106
JO - Mammalian Genome
JF - Mammalian Genome
IS - 2
ER -