Lineage tracing reveals metastatic dynamics

Eunmi Lee, Yibin Kang

Research output: Contribution to journalArticlepeer-review

Abstract

Combining single-cell lineage tracing with RNA sequencing has provided unprecedented opportunities to prospectively explore metastatic dynamics in vivo. In this issue of Cancer Cell, Simeonov et al. developed the macsGESTALT lineage recording system to reveal that hybrid EMT states and S100 expression are associated with elevated metastatic abilities in a pancreatic cancer model.

Original languageEnglish (US)
Pages (from-to)1050-1052
Number of pages3
JournalCancer Cell
Volume39
Issue number8
DOIs
StatePublished - Aug 9 2021

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cell Biology
  • Cancer Research

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