Ligand synthesis and passivation for silver and large gold nanoparticles for single-particle-based sensing and spectroscopy

Daniel Montiel, Emma V. Yates, Li Sun, Marissa M. Sampias, John Malona, Erik J. Sorensen, Haw Yang

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Silver and large gold nanoparticles are more efficient scatterers than smaller particles, which can be advantageous for a variety of single-particle-based sensing and spectroscopic applications. The increased susceptibility to surface oxidation and the larger surface area of these particles, however, present challenges to colloid stability and controllable bio-conjugation strategies. In this chapter, ligand syntheses and particle passivation procedures for yielding stable and bio-conjugatable colloids of silver and large gold nanoparticles are described.

Original languageEnglish (US)
Title of host publicationNanomaterial Interfaces in Biology
Subtitle of host publicationMethods and Protocols
PublisherHumana Press Inc.
Pages237-250
Number of pages14
ISBN (Print)9781627034616
DOIs
StatePublished - 2013

Publication series

NameMethods in Molecular Biology
Volume1025
ISSN (Print)1064-3745

All Science Journal Classification (ASJC) codes

  • Genetics
  • Molecular Biology

Keywords

  • Bio-conjugation
  • Gold nanoparticles
  • Nanoparticle passivation
  • Silver nanoparticles

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