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Leveraging antibiotic hormesis for cryptic natural product discovery
Joon Soo An
, Ellysia N. Overton
,
Mohammad R. Seyedsayamdost
Chemistry
Research output
:
Contribution to journal
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Article
›
peer-review
2
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Keyphrases
Antibiotics
100%
Natural Product Discovery
100%
Hormesis
100%
Cryptic Natural Products
100%
Cryptic Metabolite
80%
Growth Inhibition
40%
Natural Products
40%
High Dose
40%
Biosynthetic Gene Clusters
20%
Signaling Molecules
20%
Molecular Mechanism
20%
Metabolic Regulation
20%
Secondary Metabolites
20%
Therapeutic Agents
20%
Screening Approach
20%
Scalable Platform
20%
Ecological Mechanism
20%
Therapeutic Leads
20%
Microbial Natural Products
20%
Comparative Metabolomics
20%
Natural Medicine
20%
Natural Lead
20%
Microbial Metabolic
20%
Low-dose Antibiotics
20%
Scale-up Fermentation
20%
In-house Library
20%
Metabolomic Analysis
20%
Metabolite Biosynthesis
20%
Immunology and Microbiology
Metabolite
100%
Antimicrobial Agent
100%
Hormesis
100%
Low Drug Dose
60%
Drug Megadose
40%
Gene Cluster
20%
Growth Inhibition
20%
Biosynthesis
20%
Secondary Metabolite
20%
Scale up
20%
Metabolic Regulation
20%
Bacterium
20%
Inhibitory Dose
20%
Biochemistry, Genetics and Molecular Biology
Metabolite
100%
Hormesis
100%
Low Drug Dose
60%
Drug Megadose
40%
Gene Cluster
20%
Anabolism
20%
Metabolomics
20%
Scale up
20%
Growth Inhibition
20%
Secondary Metabolite
20%
Metabolic Regulation
20%
Bacterium
20%
Inhibitory Dose
20%