Irreversible assembly of membrane fusion machines

Doug Barrick, Frederick M. Hughson

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

A large kinetic barrier prevents spontaneous disassembly of SNARE complexes, complicating thermodynamic measurements and resulting in hysteresis. Nonetheless, this kinetic barrier is probably crucial for SNARE function.

Original languageEnglish (US)
Pages (from-to)78-80
Number of pages3
JournalNature Structural Biology
Volume9
Issue number2
DOIs
StatePublished - 2002

All Science Journal Classification (ASJC) codes

  • Genetics
  • Structural Biology
  • Biochemistry

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