Intricate roles of mammalian sirtuins in defense against viral pathogens

Hanna G. Budayeva, Elizabeth A. Rowland, Ileana M. Cristea

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

For a number of years, sirtuin enzymes have been appreciated as effective "sensors" of the cellular environment to rapidly transmit information to diverse cellular pathways. Much effort was placed into exploring their roles in human cancers and aging. However, a growing body of literature brings these enzymes to the spotlight in the field of virology. Here, we discuss sirtuin functions in the context of viral infection, which provide regulatory points for therapeutic intervention against pathogens.

Original languageEnglish (US)
Pages (from-to)5-8
Number of pages4
JournalJournal of virology
Volume90
Issue number1
DOIs
StatePublished - 2016

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Fingerprint Dive into the research topics of 'Intricate roles of mammalian sirtuins in defense against viral pathogens'. Together they form a unique fingerprint.

  • Cite this