Internal promoter elements of transfer RNA genes are preferentially exposed in chromatin

Robert DeLotto, Paul Schedl

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

We have examined the chromatin organization of a cluster of transfer RNA genes at the cytogenic locus 90BC on the right arm of the third Drosophila melanogaster chromosome. We find that the internal promoter sequences are preferentially exposed to micrococcal nuclease and DNase I in chromatin. Moreover, these exposed sequences have an unusual single strand nuclease-sensitive conformation.

Original languageEnglish (US)
Pages (from-to)607-628
Number of pages22
JournalJournal of Molecular Biology
Volume179
Issue number4
DOIs
StatePublished - Nov 15 1984

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Molecular Biology

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