Interactions in phospholipid-cholesterol mixed monolayers at the air/water interface

M. M. Standish, Brian Anthony Pethica

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Mixed monolayers of phospholipid and cholesterol have been studied at the air-water interface by means of surface pressure and surface potential measurements. Two synthetic phospholipids were used; di-stearoyl dl-α-phosphatidyl ethanolamine and di-myristoyl dl-α-phosphatidyl choline. Only the surface pressure results for the di-myristoyl dl-α-phosphatidyl chorine-cholesterol mixtures indicated significant deviations from ideal mixing. In addition, the surface potential results for this system indicated dipole shifts to have taken place on mixing and these data are analysed by two different methods. Published work on phospholipid-cholesterol mixed monolayers is discussed.

Original languageEnglish (US)
Pages (from-to)659-665
Number of pages7
JournalBiochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism
Volume144
Issue number3
DOIs
StatePublished - Dec 5 1967
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Endocrinology

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