Integrated production and distribution planning for industrial gases supply chains

Sérgio M.S. Neiro, Tarun Madan, José M. Pinto, Christos T. Maravelias

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


A challenge in planning the operations of multisite production networks is the need to simultaneously balance production across sites while satisfying customers demand and keeping customer service levels high and overall costs low. Accordingly, we present a planning approach for the simultaneous optimization of production and distribution operations. Specifically, we consider a regional Argon supply chain, comprised of multiple production sites and customers, in which liquid Argon is distributed through tanker trucks under cryogenic conditions. The proposed approach first generates detailed routes and then uses these routes in an integrated model to fully optimize production and distribution. Using a series of case studies, based on industrially inspired data, we show that the proposed approach leads to high quality results for regional networks of real-world sizes.

Original languageEnglish (US)
Article number107778
JournalComputers and Chemical Engineering
StatePublished - May 2022
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • General Chemical Engineering
  • Computer Science Applications


  • Coordinated production-distribution plan
  • Decomposition
  • Industrial gases
  • Inventory routing
  • Mixed-integer linear programming


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