Infection trains the host for microbiota-enhanced resistance to pathogens

Apollo Stacy; Vinicius Andrade-Oliveira; John A. McCulloch; Benedikt Hild; Ji Hoon Oh; P. Juliana Perez-Chaparro; Choon K. Sim; Ai Ing Lim; Verena M. Link; Michel Enamorado; Giorgio Trinchieri; Julia A. Segre; Barbara Rehermann; Yasmine Belkaid

doi:10.1016/j.cell.2020.12.011

Infection trains the host for microbiota-enhanced resistance to pathogens

Apollo Stacy
, Vinicius Andrade-Oliveira
, John A. McCulloch
, Benedikt Hild
, Ji Hoon Oh
, P. Juliana Perez-Chaparro
, Choon K. Sim
, Ai Ing Lim
, Verena M. Link
, Michel Enamorado
, Giorgio Trinchieri
, Julia A. Segre
, Barbara Rehermann
, Yasmine Belkaid

Research output: Contribution to journal › Article › peer-review

192 Scopus citations

Abstract

Previous intestinal infection increases the gut microbiota's resistance to subsequent infection by inhibiting the ability of pathogens to respire.

Original language	English (US)
Pages (from-to)	615-627.e17
Journal	Cell
Volume	184
Issue number	3
DOIs	https://doi.org/10.1016/j.cell.2020.12.011
State	Published - Feb 4 2021
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

Keywords

Citrobacter rodentium
Enterococcus faecalis
Klebsiella pneumoniae
aerobic respiration
bile acid
bismuth subsalicylate
colonization resistance
gut microbiome
hydrogen sulfide
taurine

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10.1016/j.cell.2020.12.011

Cite this

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title = "Infection trains the host for microbiota-enhanced resistance to pathogens",

abstract = "Previous intestinal infection increases the gut microbiota's resistance to subsequent infection by inhibiting the ability of pathogens to respire.",

keywords = "Citrobacter rodentium, Enterococcus faecalis, Klebsiella pneumoniae, aerobic respiration, bile acid, bismuth subsalicylate, colonization resistance, gut microbiome, hydrogen sulfide, taurine",

author = "Apollo Stacy and Vinicius Andrade-Oliveira and McCulloch, \{John A.\} and Benedikt Hild and Oh, \{Ji Hoon\} and Perez-Chaparro, \{P. Juliana\} and Sim, \{Choon K.\} and Lim, \{Ai Ing\} and Link, \{Verena M.\} and Michel Enamorado and Giorgio Trinchieri and Segre, \{Julia A.\} and Barbara Rehermann and Yasmine Belkaid",

note = "Publisher Copyright: {\textcopyright} 2020",

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month = feb,

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doi = "10.1016/j.cell.2020.12.011",

language = "English (US)",

volume = "184",

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T1 - Infection trains the host for microbiota-enhanced resistance to pathogens

AU - Stacy, Apollo

AU - Andrade-Oliveira, Vinicius

AU - McCulloch, John A.

AU - Hild, Benedikt

AU - Oh, Ji Hoon

AU - Perez-Chaparro, P. Juliana

AU - Sim, Choon K.

AU - Lim, Ai Ing

AU - Link, Verena M.

AU - Enamorado, Michel

AU - Trinchieri, Giorgio

AU - Segre, Julia A.

AU - Rehermann, Barbara

AU - Belkaid, Yasmine

PY - 2021/2/4

Y1 - 2021/2/4

N2 - Previous intestinal infection increases the gut microbiota's resistance to subsequent infection by inhibiting the ability of pathogens to respire.

AB - Previous intestinal infection increases the gut microbiota's resistance to subsequent infection by inhibiting the ability of pathogens to respire.

KW - Citrobacter rodentium

KW - Enterococcus faecalis

KW - Klebsiella pneumoniae

KW - aerobic respiration

KW - bile acid

KW - bismuth subsalicylate

KW - colonization resistance

KW - gut microbiome

KW - hydrogen sulfide

KW - taurine

UR - https://www.scopus.com/pages/publications/85099559534

UR - https://www.scopus.com/pages/publications/85099559534#tab=citedBy

U2 - 10.1016/j.cell.2020.12.011

DO - 10.1016/j.cell.2020.12.011

M3 - Article

C2 - 33453153

AN - SCOPUS:85099559534

SN - 0092-8674

VL - 184

SP - 615-627.e17

JO - Cell

JF - Cell

IS - 3

ER -

Infection trains the host for microbiota-enhanced resistance to pathogens

Abstract

All Science Journal Classification (ASJC) codes

Keywords

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