Increased muscle efficiency and sustained benefits in an outpatient community hospital-based pulmonary rehabilitation program

R. H.O. Holle, D. V. Williams, J. C. Vandree, G. L. Starks, R. B. Schoene

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Previous reports of pulmonary rehabilitation programs have demonstrated improvement in exercise capacity in subjects with disabling pulmonary disease. However, the cost-effectiveness, benefits to outpatients in a community setting, durability of these improvements, and mechanism of improved exercise capacity remain unclear. Forty-four patients with an average FEV1 of 33 ± 4 percent of predicted completed a six-week long period of supervised treadmill exercise, as well as a continuing home program. Twenty percent had previously unsuspected cardiac disease discovered through the program, while 36 percent had previously unsuspected exercise desaturation. Cardiopulmonary stress testing before and after the program revealed a 73 ± 16 percent improvement in aerobic capacity (METs peak [power]) and a 250 ± 78 percent improvement in endurance (MET-min [work]). No significant change was seen in V̇(E) max, HR max, FEV1, or the degree of exercise desaturation. Only a small improvement was noted in V̇(O2) max (15 ± 8 percent) and O2 pulse (16 ± 8 percent), suggesting that most of the improvement was due to improved muscle efficiency. Follow-up testing at 12 ± 3 months in 24 subjects revealed that 89 ± 7 percent of the peak exercise performance was maintained. The cost of the basic program was $800. The results demonstrated that an outpatient community hospital pulmonary rehabilitation program can accomplish substantial exercise capacity improvement with sustained benefits in a cost-effective manner.

Original languageEnglish (US)
Pages (from-to)1161-1168
Number of pages8
Issue number6
StatePublished - Jan 1 1988
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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