Increased Cocaine Motivation Is Associated with Degraded Spatial and Temporal Representations in IL-NAc Neurons

Courtney M. Cameron; Malavika Murugan; Jung Yoon Choi; Esteban A. Engel; Ilana B. Witten

doi:10.1016/j.neuron.2019.04.015

Increased Cocaine Motivation Is Associated with Degraded Spatial and Temporal Representations in IL-NAc Neurons

Courtney M. Cameron, Malavika Murugan, Jung Yoon Choi, Esteban A. Engel, Ilana B. Witten

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48 Scopus citations

Abstract

Cameron et al. report that spatial and temporal representations in IL-NAc neurons during drug seeking are degraded after a drug-free period. The disengagement of this “anti-relapse” projection may contribute to heightened drug seeking that results from a drug-free period.

Original language	English (US)
Pages (from-to)	80-91.e7
Journal	Neuron
Volume	103
Issue number	1
DOIs	https://doi.org/10.1016/j.neuron.2019.04.015
State	Published - Jul 3 2019

All Science Journal Classification (ASJC) codes

General Neuroscience

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10.1016/j.neuron.2019.04.015

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title = "Increased Cocaine Motivation Is Associated with Degraded Spatial and Temporal Representations in IL-NAc Neurons",

abstract = "Cameron et al. report that spatial and temporal representations in IL-NAc neurons during drug seeking are degraded after a drug-free period. The disengagement of this “anti-relapse” projection may contribute to heightened drug seeking that results from a drug-free period.",

author = "Cameron, \{Courtney M.\} and Malavika Murugan and Choi, \{Jung Yoon\} and Engel, \{Esteban A.\} and Witten, \{Ilana B.\}",

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AU - Murugan, Malavika

AU - Choi, Jung Yoon

AU - Engel, Esteban A.

AU - Witten, Ilana B.

PY - 2019/7/3

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N2 - Cameron et al. report that spatial and temporal representations in IL-NAc neurons during drug seeking are degraded after a drug-free period. The disengagement of this “anti-relapse” projection may contribute to heightened drug seeking that results from a drug-free period.

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Increased Cocaine Motivation Is Associated with Degraded Spatial and Temporal Representations in IL-NAc Neurons

Abstract

All Science Journal Classification (ASJC) codes

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