In vivo measurement of mid-infrared light scattering from human skin

Anna P.M. Michel, Sabbir Liakat, Kevin Bors, Claire F. Gmachl

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Two mid-infrared light sources, a broadband source from a Fourier Transform Infrared Spectrometer (FTIR) and a pulsed Quantum Cascade (QC) Laser, are used to measure angle-resolved backscattering in vivo from human skin across a broad spectral range. Scattering profiles measured using the FTIR suggest limited penetration of the light into the skin, with most of the light interacting with the stratum corneum layer of the epidermis. Scattering profiles from the QC laser show modulation patterns with angle suggesting interaction with scattering centers in the skin. The scattering is attributed to interaction of the laser light with components such as collagen fibers and capillaries in the dermis layer of the skin.

Original languageEnglish (US)
Pages (from-to)520-530
Number of pages11
JournalBiomedical Optics Express
Issue number4
StatePublished - Apr 1 2013

All Science Journal Classification (ASJC) codes

  • Atomic and Molecular Physics, and Optics
  • Biotechnology


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