In vitro processing of E. coli tRNA precursors

Paul Schedl; John Roberts; Paul Primakoff

doi:10.1016/0092-8674(76)90226-9

In vitro processing of E. coli tRNA precursors

Paul Schedl, John Roberts, Paul Primakoff

Research output: Contribution to journal › Article › peer-review

51 Scopus citations

Abstract

Using E. coli tRNA precursors isolated from an RNAase P mutant strain, we have studied the steps required for the formation of tRNAs having a mature primary sequence in vitro. Our results suggest that at least three different enzymatic activities can participate in the processing of tRNA precursors.

Original language	English (US)
Pages (from-to)	581-594
Number of pages	14
Journal	Cell
Volume	8
Issue number	4
DOIs	https://doi.org/10.1016/0092-8674(76)90226-9
State	Published - Aug 1976
Externally published	Yes

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

Access to Document

10.1016/0092-8674(76)90226-9

Cite this

@article{028c86ed33264b3e8072b8f0f634834d,

title = "In vitro processing of E. coli tRNA precursors",

abstract = "Using E. coli tRNA precursors isolated from an RNAase P mutant strain, we have studied the steps required for the formation of tRNAs having a mature primary sequence in vitro. Our results suggest that at least three different enzymatic activities can participate in the processing of tRNA precursors.",

author = "Paul Schedl and John Roberts and Paul Primakoff",

year = "1976",

month = aug,

doi = "10.1016/0092-8674(76)90226-9",

language = "English (US)",

volume = "8",

pages = "581--594",

journal = "Cell",

issn = "0092-8674",

publisher = "Elsevier B.V.",

number = "4",

}

TY - JOUR

T1 - In vitro processing of E. coli tRNA precursors

AU - Schedl, Paul

AU - Roberts, John

AU - Primakoff, Paul

PY - 1976/8

Y1 - 1976/8

N2 - Using E. coli tRNA precursors isolated from an RNAase P mutant strain, we have studied the steps required for the formation of tRNAs having a mature primary sequence in vitro. Our results suggest that at least three different enzymatic activities can participate in the processing of tRNA precursors.

AB - Using E. coli tRNA precursors isolated from an RNAase P mutant strain, we have studied the steps required for the formation of tRNAs having a mature primary sequence in vitro. Our results suggest that at least three different enzymatic activities can participate in the processing of tRNA precursors.

UR - https://www.scopus.com/pages/publications/0017186284

UR - https://www.scopus.com/inward/citedby.url?scp=0017186284&partnerID=8YFLogxK

U2 - 10.1016/0092-8674(76)90226-9

DO - 10.1016/0092-8674(76)90226-9

M3 - Article

C2 - 782726

AN - SCOPUS:0017186284

SN - 0092-8674

VL - 8

SP - 581

EP - 594

JO - Cell

JF - Cell

IS - 4

ER -

In vitro processing of E. coli tRNA precursors

Abstract

All Science Journal Classification (ASJC) codes

Access to Document

Other files and links

Fingerprint

Cite this