Improved performance of deterministic lateral displacement arrays with triangular posts

Kevin Loutherback, Kevin S. Chou, Jonathan Newman, Jason Puchalla, Robert H. Austin, James C. Sturm

Research output: Contribution to journalArticle

94 Scopus citations

Abstract

Deterministic lateral displacement arrays have shown great promise for size-based particle analysis and purification in medicine and biology. Here, we demonstrate that the use of an array of triangular rather than circular posts significantly enhances the performance of these devices by reducing clogging, lowering hydrostatic pressure requirements, and increasing the range of displacement characteristics. Experimental data and theoretical models are presented to create a compelling argument that future designs of deterministic lateral displacement arrays should employ triangular posts. The effect of practical considerations, such as vertex rounding, post size, and shape, is also discussed.

Original languageEnglish (US)
Pages (from-to)1143-1149
Number of pages7
JournalMicrofluidics and Nanofluidics
Volume9
Issue number6
DOIs
StatePublished - Dec 1 2010

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Materials Chemistry

Keywords

  • Clogging
  • Lateral displacement
  • Particle separation
  • Throughput
  • Triangular posts

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