Implications of Big Data for cell biology

Kara Dolinski, Olga G. Troyanskaya

Research output: Contribution to journalReview articlepeer-review

38 Scopus citations


"Big Data" has surpassed "systems biology" and "omics" as the hottest buzzword in the biological sciences, but is there any substance behind the hype? Certainly, we have learned about various aspects of cell and molecular biology from the many individual high-throughput data sets that have been published in the past 15-20 years. These data, although useful as individual data sets, can provide much more knowledge when interrogated with Big Data approaches, such as applying integrative methods that leverage the heterogeneous data compendia in their entirety. Here we discuss the benefits and challenges of such Big Data approaches in biology and how cell and molecular biologists can best take advantage of them.

Original languageEnglish (US)
Pages (from-to)2575-2578
Number of pages4
JournalMolecular biology of the cell
Issue number14
StatePublished - Jul 15 2015

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Cell Biology


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