Impact of virus infection on host cell protein synthesis.

R. J. Schneider, T. Shenk

Research output: Contribution to journalReview articlepeer-review

164 Scopus citations


There is good evidence that a variety of viruses encode functions that inhibit activation of either ribonuclease L or the Pl/eIF-2 alpha kinase. In general, this capability is evident among viruses that maintain long-term active or latent infections, and must therefore deal with interferon-induced antiviral responses of their hosts.

Original languageEnglish (US)
Pages (from-to)317-332
Number of pages16
JournalAnnual review of biochemistry
StatePublished - 1987

All Science Journal Classification (ASJC) codes

  • Biochemistry


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