There is good evidence that a variety of viruses encode functions that inhibit activation of either ribonuclease L or the Pl/eIF-2 alpha kinase. In general, this capability is evident among viruses that maintain long-term active or latent infections, and must therefore deal with interferon-induced antiviral responses of their hosts.
|Original language||English (US)|
|Number of pages||16|
|Journal||Annual review of biochemistry|
|State||Published - 1987|
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