Abstract
The sustained liquid flow of a typical lateral flow assay can be mimicked by two-dimensional shaped, thin porous membranes, specifically rectangular membranes appended to circular sectors. In designing these fan-shaped devices, we have been aided by analytical equations and finite-element simulations. We show both mathematically and experimentally how a continuous increase in unwetted pore volume causes a deviation from traditional imbibition, and leads to quasi-stationary flow in the rectangular element. These results are both theoretically and practically important because they indicate how medical, diagnostic test strips may be fabricated, without incorporating an absorbent pad.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1380-1385 |
| Number of pages | 6 |
| Journal | Langmuir |
| Volume | 26 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jan 19 2010 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Condensed Matter Physics
- Spectroscopy
- General Materials Science
- Surfaces and Interfaces
- Electrochemistry
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