Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals

Lu Chen; Aaron B. Wolf; Wenqing Fu; Liming Li; Joshua M. Akey

doi:10.1016/j.cell.2020.01.012

Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals

Lu Chen
, Aaron B. Wolf
, Wenqing Fu
, Liming Li
, Joshua M. Akey

Lewis-Sigler Institute for Integrative Genomics

Research output: Contribution to journal › Article › peer-review

180 Scopus citations

Abstract

Detecting archaic introgression in modern humans without using an unadmixed reference panel reveals higher Neanderthal ancestry in African individuals than previously seen and suggests that back-to-Africa migrations contributed to this signal.

Original language	English (US)
Pages (from-to)	677-687.e16
Journal	Cell
Volume	180
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2020.01.012
State	Published - Feb 20 2020

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

Keywords

Africa
IBD
Neanderthal
archaic admixture
back-migration
evolution
pre-OOA

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10.1016/j.cell.2020.01.012

Cite this

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title = "Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals",

abstract = "Detecting archaic introgression in modern humans without using an unadmixed reference panel reveals higher Neanderthal ancestry in African individuals than previously seen and suggests that back-to-Africa migrations contributed to this signal.",

keywords = "Africa, IBD, Neanderthal, archaic admixture, back-migration, evolution, pre-OOA",

author = "Lu Chen and Wolf, \{Aaron B.\} and Wenqing Fu and Liming Li and Akey, \{Joshua M.\}",

note = "Publisher Copyright: {\textcopyright} 2020",

year = "2020",

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doi = "10.1016/j.cell.2020.01.012",

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T1 - Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals

AU - Chen, Lu

AU - Wolf, Aaron B.

AU - Fu, Wenqing

AU - Li, Liming

AU - Akey, Joshua M.

PY - 2020/2/20

Y1 - 2020/2/20

N2 - Detecting archaic introgression in modern humans without using an unadmixed reference panel reveals higher Neanderthal ancestry in African individuals than previously seen and suggests that back-to-Africa migrations contributed to this signal.

AB - Detecting archaic introgression in modern humans without using an unadmixed reference panel reveals higher Neanderthal ancestry in African individuals than previously seen and suggests that back-to-Africa migrations contributed to this signal.

KW - Africa

KW - IBD

KW - Neanderthal

KW - archaic admixture

KW - back-migration

KW - evolution

KW - pre-OOA

UR - https://www.scopus.com/pages/publications/85079326987

UR - https://www.scopus.com/pages/publications/85079326987#tab=citedBy

U2 - 10.1016/j.cell.2020.01.012

DO - 10.1016/j.cell.2020.01.012

M3 - Article

C2 - 32004458

AN - SCOPUS:85079326987

SN - 0092-8674

VL - 180

SP - 677-687.e16

JO - Cell

JF - Cell

IS - 4

ER -

Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals

Abstract

All Science Journal Classification (ASJC) codes

Keywords

Access to Document

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