Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals

Lu Chen; Aaron B. Wolf; Wenqing Fu; Liming Li; Joshua M. Akey

doi:10.1016/j.cell.2020.01.012

Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals

Lu Chen, Aaron B. Wolf, Wenqing Fu, Liming Li, Joshua M. Akey

Lewis-Sigler Institute for Integrative Genomics

Research output: Contribution to journal › Article › peer-review

141 Scopus citations

Abstract

Detecting archaic introgression in modern humans without using an unadmixed reference panel reveals higher Neanderthal ancestry in African individuals than previously seen and suggests that back-to-Africa migrations contributed to this signal.

Original language	English (US)
Pages (from-to)	677-687.e16
Journal	Cell
Volume	180
Issue number	4
DOIs	https://doi.org/10.1016/j.cell.2020.01.012
State	Published - Feb 20 2020

All Science Journal Classification (ASJC) codes

General Biochemistry, Genetics and Molecular Biology

Keywords

Africa
IBD
Neanderthal
archaic admixture
back-migration
evolution
pre-OOA

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10.1016/j.cell.2020.01.012

Cite this

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title = "Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals",

abstract = "Detecting archaic introgression in modern humans without using an unadmixed reference panel reveals higher Neanderthal ancestry in African individuals than previously seen and suggests that back-to-Africa migrations contributed to this signal.",

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author = "Lu Chen and Wolf, {Aaron B.} and Wenqing Fu and Liming Li and Akey, {Joshua M.}",

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AU - Chen, Lu

AU - Wolf, Aaron B.

AU - Fu, Wenqing

AU - Li, Liming

AU - Akey, Joshua M.

PY - 2020/2/20

Y1 - 2020/2/20

N2 - Detecting archaic introgression in modern humans without using an unadmixed reference panel reveals higher Neanderthal ancestry in African individuals than previously seen and suggests that back-to-Africa migrations contributed to this signal.

AB - Detecting archaic introgression in modern humans without using an unadmixed reference panel reveals higher Neanderthal ancestry in African individuals than previously seen and suggests that back-to-Africa migrations contributed to this signal.

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KW - back-migration

KW - evolution

KW - pre-OOA

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Identifying and Interpreting Apparent Neanderthal Ancestry in African Individuals

Abstract

All Science Journal Classification (ASJC) codes

Keywords

Access to Document

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