Identification of biological microparticles using ultrafast depletion spectroscopy

Francois Courvoisier, Luigi Bonacina, Véronique Boutou, Laurent Guyon, Christophe Bonnet, Benoit Thuillier, Jerome Extermann, Matthias Roth, Herschel Rabitz, Jean Pierre Wolf

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


We show how an ultrafast pump-pump excitation induces strong fluorescence depletion in biological samples, such as bacteria-containing droplets, in contrast with fluorescent interferents, such as polycyclic aromatic compounds, despite similar spectroscopic properties. Application to the optical remote discrimination of biotic versus non-biotic particles is proposed. Further improvement is required to allow the discrimination of one pathogenic among other non-pathogenic micro-organisms. This improved selectivity may be reached with optimal coherent control experiments, as discussed in the paper.

Original languageEnglish (US)
Pages (from-to)37-49
Number of pages13
JournalFaraday Discussions
StatePublished - 2007

All Science Journal Classification (ASJC) codes

  • General Medicine


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