Hypnosis effect on carbon dioxide chemosensitivity

P. Sato, M. Sargur, R. B. Schoene

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Hypnosis is an induced state of heightened suggestibility during which certain physiologic variables can be altered. To investigate if carbon dioxide (CO2) chemosensitivity could be blunted during this suggestible state, we measured hypercapnic ventilatory response (HCVR, ΔV̇E/ΔPaCO2), oxygen consumption (V̇O2), breathing pattern (VT and f), inspiratory flow rate (VT/T(i)), and inspiratory timing (T(i)/T(tot)) in 20 healthy subjects. Mouth occlusion pressures (P0.1) were measured in the last nine subjects. Resting oxygen consumption and minute ventilation were measured during awake and hypnotic control states. The HCVR was measured spontaneously and with the suggestion to maintain normal ventilation during both wake and hypnotic conditions. It was found that without a change in metabolism, ventilatory responses to CO2 could be blunted both voluntarily, and to a greater degree, with hypnotic suggestion. These findings may have important implications in clinical settings in which patients suffer from marked dyspnea secondary to increased ventilatory chemosensitivity.

Original languageEnglish (US)
Pages (from-to)828-831
Number of pages4
JournalChest
Volume89
Issue number6
DOIs
StatePublished - Jan 1 1986
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine
  • Cardiology and Cardiovascular Medicine

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